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Game-changer: study in “Nature” reveals “consistent pathophysiological alterations” after Covid vaccination

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John O’Sullivan

November 2, 2021

A game-changer study just published in the respected journal, Nature, revealed that the experimental COVID ‘vaccines’ have only temporary benefits, but  worse yet, are long term threats to your life!  It warns, anyone vaxxed who already has poor health is especially prone to dangers from cardiovascular mortality. [1]

The stark warning from this Nature study is that it:

 “recommends additional caution when vaccinating people with pre-existing clinical conditions, including diabetes, electrolyte imbalances, renal dysfunction, and coagulation disorders.”

But don’t be complacent if you’re in rude health when you get the jab because these new results appear to suggest that even healthy people who take the vaccine may be unnecessarily exposing themselves to higher risk of developing diabetes.

A total of 11 healthy adult volunteers of both sexes, aged 24–47 years, with a BMI of 21.5–30.0 kg/m², were enrolled for the study. Adverse events were monitored daily during the first 7 days after each inoculation and then self-recorded by the participants on diary cards in the following weeks. Overall, adverse reactions were mild (grades 1 or 2) and transient (Supplementary Table S3).

The authors noted that the science and “The manner in which vaccination would mimic an infection has not been fully evaluated.”

The study confirmed that these ‘vaccines’ do not have long lasting benefit.

Antibodies production was not sustained over the long period and by the end of three months the vaccine had lost half of effectiveness, such that, “By day 90, IgG positivity also reduced to 50%, indicating antibody production did not sustain for a long time.”

The authors found:

“Testing results from cohort A demonstrated that prior to the 2nd inoculation 0 percent of the participants developed anti-SARS-CoV-2 IgG, but by day 28, which was 2 weeks post the 2nd inoculation, 100 percent of the participants were tested positive (Fig. 1b)”

The study adds:

“ PBMCs scRNA-seq results also indicated consistent reductions in CD8+ T cells and increases in monocyte contents, as well as enhanced NF-κB inflammatory signaling, which also mimicked responses after infection. Surprisingly, type I interferon responses, which had been linked to reduced damages after SARS-CoV-2 infection and milder symptoms, appeared to be reduced after vaccination, at least by 28 days post the 1st inoculation. This might suggest that in the short-term (1 month) after vaccination, a person’s immune system is in a non-privileged state, and may require more protection.”

Type 2 Diabetic Concerns

Perhaps the most worrying finding, especially for westerners eating an unhealthy high sugar diet, is the inordinate rise in blood sugar levels directly correlated to being injected with these experimental ‘vaccines.’

The study found:

“To our surprise, quite consistent increases in HbA1c levels were observed in healthy volunteers, regardless of whether they belonged to cohort A or B. By day 28 post the 1st inoculation, three out of 11 individuals reached the prediabetic range (Fig. 2c). By days 42 and 90, medium HbA1c levels appeared to revert back, yet were still significantly higher than those before vaccination. Previous work has demonstrated that diabetic patients with uncontrolled blood glucose levels are more prone to develop severe forms of COVID-1919. High blood glucose levels/glycolysis had been shown to promote SARS-CoV-2 replication in human monocytes via the production of mitochondrial reactive oxygen species and activation of HIF1A20, therefore presenting a disadvantageous feature.”

What is HbA1c?

HbA1c is what’s known as glycated haemoglobin. This is something that’s made when the glucose (sugar) in your body sticks to your red blood cells. Your body can’t use the sugar properly, so more of it sticks to your blood cells and builds up in your blood.

Risks from higher HbA1c

It is known among medical scientists that:

“High HbA1c levels can have many negative effects on your health, whether you have diabetes or not. People with high levels are at an increased risk of dementia, heart disease, kidney disease, mental health problems, fatigue, and bone loss. Scientists think HbA1c levels might also impact a person’s lifespan. Both above and below normal levels have been linked with increased mortality.”[2]

It doesn’t take a medical expert to grasp the significance of this; having these experimental jabs is now proven to likely increase your risk of a range of life-threatening diseases. So, choose to be a Big Pharma guinea pig at your peril!



About John O’Sullivan John is CEO and co-founder (with Dr Tim Ball) of Principia Scientific International (PSI).  John is a seasoned science writer and legal analyst who assisted Dr Ball in defeating world leading climate expert, Michael ‘hockey stick’ Mann in the ‘science trial of the century‘. O’Sullivan is credited as the visionary who formed the original ‘Slayers’ group of scientists in 2010 who then collaborated in creating the world’s first full-volume debunk of the greenhouse gas theory plus their new follow-up book.


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