Phase 1 study of quadrivalent flu vaccine (mRNA-1010) successfully boosted titers against all four strains in older and younger adults, even at lowest dose; no significant safety concerns were observed
Phase 2 dose-confirmation study was fully enrolled in November (N=500); preparation for Phase 3 study underway
Seasonal flu program now moving beyond quadrivalent: announcing mRNA-1011 & mRNA-1012 development candidates
moderna-announces-first-participant-dosed-phase-12-study-its
Yahoo News – US biotech company Moderna on Friday announced promising data from an early-stage human trial of its mRNA flu shot, based on the same technology used in its Covid-19 vaccine.
The experimental flu shot was found to be safe, and successfully evoked high levels of antibodies in 180 people at all dosage levels, in both younger and older adults.
“Even before the Covid-19 pandemic, approximately three million people died each year due to respiratory infections, and many more are hospitalized or become ill as a result of these viruses,” said Moderna CEO Stephane Bancel in a statement hailing the result.
Side effects were mild, and occurred more often in younger than older adults. The most common included pain and tenderness at the injection site, as well as headaches, muscle and joint aches, and tiredness.
yeah mRNA flu vaccines are gonna be a hard pass for me unless they are markedly superior — the level of side effects I have from the covid shots is nearly as bad as flu and nearly as long anyways, sooo
— the gender out of space (@butts_4_jesus) December 10, 2021
mRNA “vaccines” created by Moderna and Pfizer are gene therapies. They fulfill all the definitions of gene therapy and none of the definitions for a vaccine.
— Dead Ferrets (@Deadferrets) December 10, 2021
The next stage of the trial, involving 500 people, began last month, and aims to firm up the right dosage level and compare the Moderna flu vaccine to already-licensed shots developed using more traditional methods. Interim results are expected in early 2022. Read More
Never fear, @pfizer also has a clinical trial mRNA flu vaccine in the works. Why do we still have ppl who can't see what they are doing to our bodies? It is GENE THERAPY….aka, tampering with your DNA . https://t.co/3HG5j17P5d
— Mom of 2 (@adcinde) December 10, 2021